Living with depression that does not respond to medication can leave you feeling discouraged. You may have tried different prescriptions, dose changes, or treatment approaches, only to feel as if nothing has truly helped. Over time, it may become clear that additional treatment options could support your continued progress.
Learning what to expect with Spravato may help you find a different way forward. Spravato is an FDA-approved esketamine nasal spray treatment for adults who are exploring advanced options for the treatment of depression, and it is often used alongside an oral antidepressant. Understanding how Spravato works and what the process involves can help you feel more confident and supported as you consider your next step.
Administering Spravato is a structured and carefully monitored process designed to keep you safe and supported, and the treatment follows a clear schedule. During the initial phase, most people attend two sessions a week for four weeks. After that, visits usually decrease to once a week and later may shift to every other week depending on how you respond. This gradual change allows your provider to adjust your treatment plan according to your needs. As you move through these Spravato treatment stages, you will grow more familiar with what to expect, and you may notice improvements with each successive esketamine nasal treatment.
Treatment takes place in our office under medical supervision, although you can self-administer the medication with a trained clinician present. You will then stay in the office for at least two hours so your care team can monitor your blood pressure and overall response. Safety is always our priority, and you will need a ride home after each session.
Many people want to know how Spravato sessions will feel. During treatment, you may notice sensations such as lightheadedness, changes in perception, or a feeling of detachment from your surroundings. Some people describe this as dissociation. These effects usually peak within the first hour following treatment before gradually wearing off.
You may also experience mild side effects such as nausea, sleepiness, or a headache. Your care team will check in with you throughout treatment sessions and make adjustments to keep you comfortable. Talking through the expected outcomes of Spravato treatments ahead of time often helps reduce anxiety around these sensations.
After the session, you may feel tired or unfocused for the rest of the day. We advise you not to drive, work, or make important decisions until the day after treatment. In time, many clients notice changes in mood and the manageability of daily experiences. Small tasks may feel more controllable, and moments of relief may become more frequent as treatment continues.
The frustration of living with symptoms that do not improve can take an emotional toll. Understanding what to expect with Spravato allows you to find relief from your depressive symptoms and experience improved wellness.
If you feel unable to make progress and unsure about what comes next, Spravato may be right for you. Our office is here to answer your questions, talk through your concerns, and help you decide if this treatment is right for you. You deserve a care plan that prioritizes your needs and offers clear options. Contact our team at The Neuropsychiatry & TMS Group today to schedule an appointment and take action toward feeling better.